ChemBK
  • Home
  • Product Category

1-AMINOGUANIDINE HYDROGEN CARBONATE

Aminoguanidine bicarbonate

CAS: 2582-30-1

Molecular Formula: C2H8N4O3

  1. Home
  2. Product Category
  3. intermediate
  4. pharmaceutical intermediates
  5. 1-AMINOGUANIDINE HYDROGEN CARBONATE

1-AMINOGUANIDINE HYDROGEN CARBONATE - Names and Identifiers

Name Aminoguanidine bicarbonate
Synonyms Aminoguanidine hicarbonate
1-aminoguanidine carbonate
Aminoguanidine bicarbonate
GUANYLHYDRAZINE BICARBONATE
Aminoguanidine bicarbonate
Aminoguanidine carbonic acid
1-AMINOGUANIDINE BICARBONATE
Aminoguanidine hydrogen carbonate
1-AMINOGUANIDINE HYDROGEN CARBONATE
aminoguanidinium hydrogen carbonate
1-AMINOGUANIDINIUM HYDROGEN CARBONATE
AMINOGUANIDINE BICARBONATE CRYSTALLINE
1-AMINOGUANIDINIUM HYDROGEN CARBONATE OE
CAS 2582-30-1
EINECS 219-956-7
InChI InChI=1/CH6N4.CH2O3/c2-1(3)5-4;2-1(3)4/h4H2,(H4,2,3,5);(H2,2,3,4)/p-2
InChIKey OTXHZHQQWQTQMW-UHFFFAOYSA-N

1-AMINOGUANIDINE HYDROGEN CARBONATE - Physico-chemical Properties

Molecular FormulaC2H8N4O3
Molar Mass136.11
Density1,6 g/cm3
Melting Point170-172°C (dec.)(lit.)
Boling Point422.4°C at 760 mmHg
Flash Point209.3°C
Water Solubility<5 g/L (20 ºC)
Solubility H2O: soluble2.7g/L at 20°C
Vapor Presure2.56E-08mmHg at 25°C
AppearanceCrystalline Powder
ColorWhite to off-white
BRN3569869
pKa6.19[at 20 ℃]
PH8.9 (5g/l, H2O, 20℃)
Storage ConditionStore below +30°C.
Physical and Chemical PropertiesWhite fine crystalline powder. Soft, practically insoluble in water. Insoluble in alcohol and other acids. It is unstable when heated, and gradually decomposes when it exceeds 50 ° C., turns red when it is heated to 100 ° C. In an oil bath, and decomposes completely when it is heated to 171-173 ° C. As shown in Fig.
UseIt can be used as raw materials for the synthesis of pharmaceuticals, pesticides, dyes, foaming agents and explosives.

1-AMINOGUANIDINE HYDROGEN CARBONATE - Risk and Safety

Risk CodesR52/53 - Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. 
R43 - May cause sensitization by skin contact
R36/37/38 - Irritating to eyes, respiratory system and skin.
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. 
Safety DescriptionS22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
S37 - Wear suitable gloves.
S24 - Avoid contact with skin.
S36 - Wear suitable protective clothing.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37 - Wear suitable protective clothing and gloves.
UN IDsUN3077
WGK Germany2
RTECSFG1772000
TSCAYes
HS Code29280090
Hazard Class9
Packing GroupIII
ToxicityLD50 orally in Rabbit: > 5000 mg/kg

1-AMINOGUANIDINE HYDROGEN CARBONATE - Nature

Open Data Verified Data

White fine crystalline powder. Soft, practically insoluble in water, insoluble in alcohol and other acids. Heating is not stable, when more than 45 degrees Celsius is gradually decomposed, melting point of 170~172 degrees Celsius. If it is heated slowly, it can be melted. When it is heated to 171~173 ° C in an oil bath, it will be completely decomposed. The decomposition products are soluble in water and can be decomposed by other acids, free aminoguanidine is formed and dissolved in water.

Last Update：2024-01-02 23:10:35

1-AMINOGUANIDINE HYDROGEN CARBONATE - Preparation Method

Open Data Verified Data

there are the following process routes.

  1. with lime nitrogen, hydrazine hydrate, ammonium bicarbonate as the main raw material. The distilled water is added to the lime nitrogen, the temperature is kept at 45~50 ℃ for 6 hours, the waste residue is filtered off to obtain the calcium cyanamide solution, and then dilute sulfuric acid is added to adjust the pH value to 6~7, after cooling to room temperature and filtering, the cyanamide solution is obtained, in which 5% hydrazine hydrate is added, and the temperature is kept at 50 ° C. For 4 hours, then ammonium bicarbonate is added, and the crystal is precipitated, filter dry is aminoguanidine bicarbonate crude. Then add acetic acid to dissolve the crude product, add oxalic acid, filter off calcium oxalate, adjust the pH value of the solution to 8~9 with ammonia water, and add a small amount of EDTA disodium salt, the filtered filtrate is reacted with the filtered ammonium bicarbonate solution, placed, crystallized, filtered, washed with distilled water and ethanol respectively, and finally dried by filtration to obtain a finished product.
  2. aminoguanidine bicarbonate can also be obtained by reacting cyanamide with hydrazine sulfate and then adding an aqueous solution of sodium bicarbonate to the reaction.
Last Update：2022-01-01 10:37:29

1-AMINOGUANIDINE HYDROGEN CARBONATE - Use

Open Data Verified Data

This product can be used as a synthetic raw material for medicine, pesticide, dye, photographic agent, foaming agent and explosive.

Last Update：2022-01-01 10:37:29

1-AMINOGUANIDINE HYDROGEN CARBONATE - Safety

Open Data Verified Data
  • This product is toxic. Rats after long-term inhalation concentration of 42. 6mg/m3 and poisoning, the content of hemoglobin and lymphocytes were reduced, thyroid function was inhibited. Fully indicate that this product has a certain toxicity, production and operation should take the necessary Protection Measure, to ensure safety.
  • refer to guanidine hydrochloride
    • for packaging, storage and transportation of this product
Last Update：2022-01-01 10:37:30

1-AMINOGUANIDINE HYDROGEN CARBONATE - Reference Information

LogP-6.61 at 25℃
EPA chemical information Information provided by: ofmpub.epa.gov (external link)
use can be used as a synthetic raw material for medicine, pesticide, dye, foaming agent and explosive
this product can be used as a synthetic raw material for medicine, pesticide, dye, photographic agent, foaming agent and explosive.
production method 1. made from lime nitrogen, hydrazine hydrate, ammonium bicarbonate or sodium bicarbonate. First, distilled water is added to lime nitrogen, kept at 45-50 ℃ for 6 hours, waste residue is filtered to obtain cyanamide (calcium) solution, then dilute sulfuric acid is added to cyanamide (calcium) solution to pH = 6-7, cooled to room temperature, and calcium sulfate is filtered to obtain cyanamide solution. Then 5% hydrazine hydrate is added to cyanamide solution, kept at 50 ℃ for 4 hours, then ammonium bicarbonate is added, and crystals are precipitated, filter to dry is crude aminoguanidine bicarbonate. Dissolve the crude with acetic acid, add oxalic acid, filter to remove calcium oxalate, adjust the solution to pH = 8-9 with ammonia water, add a little EDTA disodium, filter to be clear, then add filtered ammonium bicarbonate solution, place, crystallize, filter to dry, wash with distilled water and ethanol respectively, and filter to dry to obtain the finished product. 2. Condensation reaction of methyl isothiourea sulfate, hydrazine hydrate and sodium bicarbonate: dissolve methyl isothiourea sulfate in water, add hydrazine hydrate dropwise at room temperature, continue to stir for 1.5h after addition, and filter. The filtrate is concentrated to 2/5 of the original volume under reduced pressure, then the pH is adjusted to 5 with acetic acid, cooled to below 30 ℃, saturated bicarbonate solution is added under stirring, the material is released after stirring for 2 hours, cooled overnight, filtered, the filter cake is first washed with water, then washed with ethanol, and dried at 50 ℃ to obtain aminoganidine bicarbonate. Yield 85%-90%. 3. Use cyanamide and hydrazine sulfate to react, and then add sodium bicarbonate aqueous solution to react, and aminoguanidine bicarbonate can also be prepared.
spontaneous combustion temperature 245°C
Last Update：2024-04-09 21:21:28
1-AMINOGUANIDINE HYDROGEN CARBONATE
Supplier List
Nantong Reform Petro-Chemical CO., LTD.
Spot supply
Product Name: Aminoguanidine bicarbonate Request for quotation
CAS: 2582-30-1
Tel: +86-17551318830
Email: r@reformchem.com­
Mobile: +86-17551318830
QQ: 3785839865 Click to send a QQ messageSend QQ message
Jiangsu Pules Biotechnology Co.,Ltd.
Product Name: Aminoguanidine bicarbonate Request for quotation
CAS: 2582-30-1
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: Aminoguanidine bicarbonate Request for quotation
CAS: 2582-30-1
Tel: 0086-551-65418684
Email: sales@tnjchem.com
　　　　 info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840 Click to send a QQ message
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Wuhan Xingzhongcheng Chemical limited company
Spot supply
Product Name: Aminoguanidine bicarbonate Request for quotation
CAS: 2582-30-1
Tel: 86+027-83389957
Email: 1024042217@qq.com
Mobile: 86+18627766980
QQ: 1024042217 Click to send a QQ message
Wechat: 18627766980
Shanghai Worldyang Chemical Co.,Ltd.
Product Name: Aminoguanidine bicarbonate Request for quotation
CAS: 2582-30-1
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228 Click to send a QQ message
Wechat: 13651600618
WhatsApp: +8613651600618
Hangzhou Verychem Science And Technology Co.Ltd
Product Name: Aminoguanidine bicarbonate Request for quotation
CAS: 2582-30-1
Tel: +86-571-88162785
Email: Lucy@verypharm.com
Mobile: +86-13606544505
QQ: 472954302 Click to send a QQ message
Product List: View Catalog
Nantong Reform Petro-Chemical CO., LTD.
Spot supply
Product Name: Aminoguanidine bicarbonate Request for quotation
CAS: 2582-30-1
Tel: +86-17551318830
Email: r@reformchem.com­
Mobile: +86-17551318830
QQ: 3785839865 Click to send a QQ messageSend QQ message
Jiangsu Pules Biotechnology Co.,Ltd.
Product Name: Aminoguanidine bicarbonate Request for quotation
CAS: 2582-30-1
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: Aminoguanidine bicarbonate Request for quotation
CAS: 2582-30-1
Tel: 0086-551-65418684
Email: sales@tnjchem.com
　　　　 info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840 Click to send a QQ message
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Wuhan Xingzhongcheng Chemical limited company
Spot supply
Product Name: Aminoguanidine bicarbonate Request for quotation
CAS: 2582-30-1
Tel: 86+027-83389957
Email: 1024042217@qq.com
Mobile: 86+18627766980
QQ: 1024042217 Click to send a QQ message
Wechat: 18627766980
Shanghai Worldyang Chemical Co.,Ltd.
Product Name: Aminoguanidine bicarbonate Request for quotation
CAS: 2582-30-1
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228 Click to send a QQ message
Wechat: 13651600618
WhatsApp: +8613651600618
Hangzhou Verychem Science And Technology Co.Ltd
Product Name: Aminoguanidine bicarbonate Request for quotation
CAS: 2582-30-1
Tel: +86-571-88162785
Email: Lucy@verypharm.com
Mobile: +86-13606544505
QQ: 472954302 Click to send a QQ message
Product List: View Catalog
View History
1-AMINOGUANIDINE HYDROGEN CARBONATE
  • Home
  • Product Category

© 2015, 2023 ChemBK.com All Rights Reserved | Build: 20230617001